Hotels
- Country Inn & Suites by Radisson, Wytheville, VaCountry Inn & Suites by Radisson, Wytheville, Va24 hours697 Peppers Ferry Road
- Surestay Plus Hotel by Best Western WythevilleSurestay Plus Hotel by Best Western Wytheville24 hoursVirginia, Wythe County, Wytheville
- Oyo Hotel Wytheville I-77 & I-81Oyo Hotel Wytheville I-77 & I-81Business hours unknownVirginia, Wythe County, Wytheville, East Main Street
- The Bolling Wilson Hotel, Ascend Hotel CollectionThe Bolling Wilson Hotel, Ascend Hotel Collection24 hoursVirginia, Wythe County, Wytheville, East Main Street
- Ramada WythevilleRamada WythevilleBusiness hours unknownVirginia, Wythe County, Wytheville
